Figure 2: Genomic analysis reveals that mitochondrial genes are regulated by PGC-1α and mTOR pathways by means of the transcription factor YY1. Figure 3: YY1 regulates mitochondrial gene ...

The regulation of mammalian target of rapamycin (mTOR) pathway is crucial for both ... T372R mutations in the transcription factor YY1 (Yin Yang 1) by whole exome sequencing, and validate this ...

Can you please give a brief introduction to the mechanistic target of rapamycin (mTOR) cellular pathway and how it was first discovered? The mTOR pathway is probably the main pathway in humans and ...

Overactive mTOR Plays a Key Role in Aging and Alzheimer’s Disease. Simufilam Suppresses Overactive mTOR, Suggesting a Beneficial Drug Effect. Research is Published in Frontiers in Aging ...

The results suggested that mechanistic target of rapamycin (mTOR) inhibition is a potential therapeutic avenue for sarcoidosis, which the authors said should be explored in larger clinical trials.

In particular, the authors focus on the role of the mammalian Target of Rapamycin (mTOR) pathway. Herein, researchers used PubMed and Scopus databases to obtain articles related to diabetes and ...

B cells, a type of white blood cell responsible for producing antibodies, develop through several stages: common lymphoid progenitors, pre-pro-B cells, pro-B cells, pre-B cells, immature B cells ...

What is the most troublesome side effect of mTOR inhibitors? In my opinion, pneumonitis is the most troublesome side effect as it can be medically very dangerous if not identified and treated early.