Researchers from the University of Toronto, directed by Drs. Gelareh Zadeh and Boris Krischek, investigated gene expression in normal vestibular nerves and vestibular schwannomas (VSs). Two ...

2) the overexpressed PI3K/AKT/mTOR signaling pathway in these tumors ... they are generally associated with a genetic disorder, neurofibromatosis Type 2 (NF2), which is categorized by numerous ...

Neurofibromatosis is a group of rare genetic disorders that cause benign tumors to form on nerve tissue. Tumors in this disorder are usually noncancerous (benign), but can sometimes become ...

The results suggested that mechanistic target of rapamycin (mTOR) inhibition is a potential therapeutic avenue for sarcoidosis, which the authors said should be explored in larger clinical trials.

Overactive mTOR Plays a Key Role in Aging and Alzheimer’s Disease. Simufilam Suppresses Overactive mTOR, Suggesting a Beneficial Drug Effect. Research is Published in Frontiers in Aging ...

It’s important to know that an accurate diagnosis of NF2 can only be made by a physician with expertise in the diagnosis and treatment of neurofibromatosis. Specific diagnostic criteria have been ...

Our discussion this month focuses on the recent change in nomenclature for the conditions formerly known as NF2 and schwannomatosis. The change in naming conventions for these two disorders is the ...