In this way, cofilin functions only to generate G-actin to sustain steady-state ARP2/3 complex-mediated dendritic nucleation of actin polymerization at the leading edge of the cell 69.

We use in vitro as well as in vivo transcription assays to understand how exactly actin and myosins are involved in this specific process. Other research projects are directed at understanding the ...

Actomyosin is a protein complex composed of actin and myosin. It is found in muscle fibers where it plays a role in muscle contraction. Actin is one of the most abundant proteins in eukaryotes. It ...

Advance in understanding actin sheds light on cell function Atomic level insight into proteins furthers fundamental understanding of human life Date: April 13, 2020 Source: University of ...

Actin, a protein with a well-known job in the cytoplasm and an active role in muscle contraction, moonlights in the nucleus. It's function there was not understood, but now scientists find that it ...

Shot can act as a molecular linker between microtubules and actin during dendrite pruning, suggesting an intriguing role in non-centrosomal microtubule organization. However, the experimental evidence ...

Lara-Jane Kepser, Fidan Damar, Teresa De Cicco, Christine Chaponnier, Tomasz J. Prószynski, Axel Pagenstecher, Marco B. Rust, CAP2 deficiency delays myofibril actin cytoskeleton differentiation and ...

News Release 28-Aug-2024 The functions of actin-binding proteins are regulated by the flexibility and specific helical twists of actin filaments Peer-Reviewed Publication ...