Correspondence Published: November 2009 Cyclin-dependent kinases: a family portrait Marcos Malumbres, Edward Harlow, Tim Hunt, Tony Hunter, Jill M. Lahti, Gerard Manning, David O. Morgan, Li-Huei ...

In vitro, mitogen-activated protein kinase and especially cyclin B-Cdc2, but not the polo-like kinase 1, remove cyclin E-Cdk2 from chromatin. Rebinding of hyperphosphorylated cyclin E-Cdk2 to ...

However, once CDK was activated, the nucleus could tolerate decreases in cyclin without slipping out of mitosis. In contrast, a much smaller amount of cyclin could activate CDK in the cytoplasm.

Narender Kumar ², Renee Dale, Daniel Kemboi ³, Elizabeth A. Zeringue, Naohiro Kato, John C. Larkin, Functional Analysis of Short Linear Motifs in the Plant Cyclin-Dependent Kinase Inhibitor SIAMESE, ...

Cyclin E mRNA: Assessing Cyclin-Dependent Kinase (CDK) Activation State to Elucidate Breast Cancer Resistance to CDK4/6 Inhibitors The following represents disclosure information provided by authors ...