In vitro, omalizumab and human IgE form several immune complexes that vary in size as the 2 components' molar ratios are changed. [29] The largest complex, a stable cyclical hexameric structure ...

Longitudinal evaluation of SNOT-22 can distinguish patients with chronic rhinosinusitis with nasal polyps who respond quickly ...

CHRONIC spontaneous urticaria (CSU) is a distressing inflammatory skin condition characterised by the recurrent appearance of hives, angioedema, or both, lasting more than six weeks without an ...

A third study provided additional safety data and evaluated dupilumab in patients aged 12 years and older who were inadequate responders or intolerant to anti-IgE therapy and symptomatic despite ...

Remarkable progress has been made in recent years on the structural determination of proteins in the IgE network and on the functions and regulation of IgE. This is beginning to feed into IgE ...

1 A clinical history of gastrointestinal, skin or respiratory symptoms suggestive of allergy frequently results in allergen-specific IgE testing. The IMMULITE ® 2000/2000 XPi 3gAllergy ...

Methods: MEDLINE, In-Process & Other Non-Indexed Citations, and EMBASE Drugs & Pharmacology were searched using olizumab, omalizumab, E25, rhuMAb-E25, and anti-IgE. Combinations of rhinitis ...