For the first time, researchers have identified a protein that represses the activity of energy-burning brown fat. The ...

Obesity, diabetes and cardiovascular diseases are increasingly present in the population. Brown adipose tissue has a ...

Specifically, as the Osbourn group described in a recent paper, they identified CCL1, which generates the branched short-chain acyl-CoA molecule 2-MB-CoA, as the starting substrate to ...

Fatty acid oxidation is a cyclical process, where a two-carbon unit (acetyl CoA) is broken off a larger acyl-CoA molecule – the process then iterates until the precursor is completely oxidized.

Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is a genetic condition that prevents the body from breaking down fat stores for energy. It can be fatal without early diagnosis and treatment.

Prospective surveillance study of medium-chain acyl-CoA dehydrogenase deficiency in the UK. Arch Dis Child 1998;79:116-119. Crossref. PubMed. Web of Science. Google Scholar. 4.