Most-abundant zymogen granule proteins. ‡ Different isoforms present in zymogen granules. § Validated by morphological studies after identification by mass spectrometry. As the molecular ...

Here we report exocytosis of zymogen granules, as examined by multiphoton excitation imaging in intact pancreatic acini. Cholecystokinin induces Ca2+ oscillations that trigger exocytosis when the ...

Pancreatic acinar cells lacking VAMP8 had many more zymogen granules than control acinar cells. In addition, CCK did not stimulate exocytosis in VAMP8-deficient acinar cells.

In contrast, the acinar cytoplasm after 2-day administration of sorafenib was totally eosinophilic. The typical findings of acute pancreatitis were not seen in the both group. By EM examination, ...

The team coined the new form of autophagy "zymophagy" because the dangerous components that get gobbled up are called zymogen granules. "Therefore, a self-eating event within the cell protects the ...

(E) Representative acinar atrophy and decreased zymogen granules indicated by arrowheads. (F) Epithelium mucus secretory cell metaplasia indicted by arrows in Alcian blue (AB) stain.

Zymogen AX 50/15/1/1.5mg/5ml - 100 ml Syrup (Guaifenesin) drug information. Find its price or cost, dose, when to use, how to use, side effects, adverse effects, substitutes . It is manufactured ...

Zymogen granules--specialized storage organelles in the pancreas that control enzyme secretion-- play an important role in pancreatic injury and disease, but their mechanism is poorly understood.