Cryo-EM can also visualize larger structures than NMR or crystallography can: Cryo-EM specialist Sarah Butcher of the University of Helsinki estimates that the technique can analyze 100-fold ...

In-cell NMR: A new application Date ... in-cell NMR can fill a critical gap between in vitro-oriented structural techniques such as NMR spectroscopy, X-ray crystallography and single-particle cryo ...

The research group plans to further improve the integration of the techniques of cryo-EM with X-ray imaging and diffraction at X-ray free-electron laser and synchrotron facilities. The use of AI in ...

Relatively recent advances in resolution have meant that cryo-EM is able to effectively solve protein structures that were not previously possible using traditional methods like NMR and X-ray ...

Collaboration combines electron microscopy, NMR and X-ray diffraction methods to provide advances in structural biology using cryo-EM to accelerate discoveries about the causes, treatments and cures ...

Single-particle cryo-EM is an analytical technique used to deduce the 3D structure of macromolecules (particularly proteins) as an alternative to X-Ray crystallography.

To understand how this antibody hinders the spike protein, and to gather the information necessary to reproduce it, the team used cryo-electron microscopy (cryo-EM) and X-ray crystallography ...

Although initially X-ray crystallography was commonly used, the much more versatile EM is now the standard approach in the form of cryo-EM, with recent advances giving us unprecedented looks at ...

In a topical review IUCrJ (2017), 4, 108-118 Lucia Banci and her co-worker Enrico Luchinat , both based at the University of Florence, summarise the major advances of in-cell NMR and report the ...