We found that only two of 19 Wnt genes, Wnt2 and Wnt9b, were functionally present in the liver. We also found that Wnt2 and ...

Sclerosteosis arises from mutations in the SOST gene, causing abnormally high bone mass and skeletal overgrowth, which can ...

In addition, Wnt research has covered the spectrum of model ... mutations in WNT4 and aberrant expression of the target gene PKD1 (polycystic kidney disease 1).

Sclerosteosis is a rare genetic disorder that causes excessive bone growth, leading to life-altering complications, including hearing loss and facial paralysis.

Headon’s team ultimately found that fingerprints start out looking very similar to hair follicles: Both begin as small discs of cells on the epithelium, and in both cases, the cells turn on genes for ...

Through the study, Dr. Lin's team identified several key genetic alterations specific to CRC, including mutations in pathways ...

This study fills a crucial gap in our understanding of blood cell formation from human pluripotent stem cells (hPSCs). Genome-wide comparisons of hPSC-derived blood progenitor cells with in vivo blood ...

I currently investigate the role of the Wnt gene signalling pathways in vascular disease (intimal thickening), in particular in smooth muscle cells' proliferation. Previously, I have looked into the ...