With the 2025 meta in mind, here are the best runes support mains should prioritize in their next League of Legends game.

Engrave your helm with the Advanced Warding rune: Increases the magnitude of your Mana Shield, Frost Ward, and Fire Ward by 100%, and decreases mana drained by Mana Shield by 50% per damage done.

Upon completing The Wild Gods quest, the Shadowtooth Emissary turns into a vendor and players will be awarded with a new Rune for their efforts. The type of Rune depends on the player's class.