Ordinarily, HIF-mediated induction of VEGF would provide a rapid and direct mechanism to protect motor neurons during such periods of mild hypoxia. But deletion of the HRE element in the VEGF gene ...
In tissues, hypoxia causes local activation of the HIF (hypoxia-induced factor ... capillary vessels through endothelial growth factor (VEGF), a process that would bring more growth factors ...
US pharma giant Merck & Co today announced that the European Commission (EC) has conditionally approved two indications for Welireg (belzutifan), its oral hypoxia-inducible factor-2 alpha (HIF-2α) ...