TNFR1 associated death domain protein (TRADD) contains an N-terminal TRAF binding domain and a C-terminal death domain along with nuclear import and export sequences that cause shuttling between ...

All TRAF proteins share a C-terminal homology region termed the TRAF domain that is capable ... interaction with the death domain of TNFR1. This capacity for TRADD to initiate two divergent ...

Unique Role Of Cell Death Protein TRADD In Viral Signaling Date: January 14, 2008 Source: PLoS Biology Summary: A unique Epstein Barr virus-derived protein interaction domain uses the cellular ...

Cellular death is vital for health. Without it, we could develop autoimmune diseases or cancers. But a cell’s decision to self-destruct is tightly regulated, so that it only happens to serve the best ...

Nanjing Reju Therapeutics Inc. has described tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) inhibitors reported to be useful for the treatment of inflammatory-related ...