Tophi can affect any joint, including in the fingers and thumbs. It is a sign of advanced or chronic gout. When tophi affect the small joints of the thumbs and fingers, physical changes and ...

Her general practitioner diagnosed gouty arthritis because of a high serum uric-acid level (600 µmol/l; normal range 270–380 µmol/l) coexistent with tophi in her hands, and initiated ...

Tophi are a collection of uric acid crystals ... However, not all people with high uric acid levels will develop gout. Hand ...

However, given the likely contribution of higher comorbidities to poorer health outcomes among respondents, comorbid status may be confounded with gout flares and tophi in the analyses.

and dissolve tophi in gout and tophaceous gout patients, today announced that it has dosed the first patient in REDUCE 1, the Company's second pivotal Phase 3 clinical trial evaluating AR882.

Gout can be extremely painful and can affect other joints including the ankle, fingers, elbows ... of urate crystals in bumps or nodules called tophi which generally are not painful but during ...

and dissolve tophi in gout and tophaceous gout patients, today announced the completion of enrollment for its pivotal global Phase 3 REDUCE 2 trial. "We would like to thank the gout community for ...