Leg cramps—often referred to as a charley horse—are painful, involuntary contractions of the muscles in your thigh or calf. They commonly occur from dehydration or muscle overexertion.

If you have nocturnal (nighttime) leg cramps, your doctor might prescribe quinine (Qualaquin)-even though the U.S. Food and Drug Administration has approved it for only one purpose: to treat ...

Regularly experiencing leg cramps can cause discomfort and distress because of the intense pain it may induce. A powerful method to relieve leg cramps may be to incorporate magnesium supplements ...

The muscle — usually the calf at the back of the lower leg — tightens and spasms. Nocturnal leg cramps are common, with a high prevalence in older people. Many people with PAD are asymptomatic.