Like Th1 and Th2 cells, Th17 cells produce a group of distinctive cytokines — interleukin-17 (also called interleukin-17A), interleukin-17F, interleukin-22, and interleukin-21 — all of which ...

In a new study, researchers report the potent anti-tumor properties of hybrid Th1/Th17 cells that combine the cancer-fighting properties of Th1 cells and the ability of Th17 cells to self-renew ...

"In contrast to CD8 + or Th1 cells, we discovered Th17 cells could be expanded to large numbers without compromising their therapeutic quality," Paulos explains. "Th17 cells have a natural ...

Mice with EAE are often used as animal models in the study of MS. To find out how the Th1 and Th17 immune cells get across the blood-brain barrier in MS, the team genetically labeled the tight ...

Non-Th2-driven obesity-linked asthma has also been reported, with neutrophilic preponderance and hallmark increases in Th1 and Th17 cells. Obesity is also related to other conditions, including ...

NF-κB intracellular signaling is heightened in antigen-presenting cells, neutrophils, and Th1 and Th17 cells. 24,29–31 Shown are the affected organs and the frequency of clinical manifestations ...

Myasthenia gravis (MG) is a rare, chronic autoimmune disorder that disrupts the communication between nerves and muscles. It ...

SCFAs promote immune tolerance in the gut lymphatic tissues by suppressing Th1/Th17 cells and inducing regulatory T-cells. The spontaneous and induced models of EAU have been utilized to ...