1 Th1 cells primarily produce interferon (IFN)-g and interleukin (IL)-2, whereas Th2 cells produce IL-4, IL-5, IL-6, IL-10, and IL-13. The two helper T cell classes also differ by the type of immune ...
Effects of Vitamin D on Immune Disorders With Special Regard to Asthma, COPD and Autoimmune Diseases
Some of them are described below. Suppression of Th1 functions should shift the balance of Th1 versus Th2-mediated functions toward the Th2 cells. [50] Thus, VD should aggravate the Th2-mediated ...
For example, activated T helper type 1 lymphocytes secrete interferon (IFN)-γ, which has potent effects on osteoclastogenesis in vivo and in vitro. IFN-γ, however, is known to cause both bone ...
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Researchers gain new understanding of how immune cells respond to heat during feverThe modified Th1 cells activate interferon and p53 genes. The p53 protein repairs DNA and contributes to genomic integrity. Interferon genes enhance T-cell effector function, or the ability to ...
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