Some of them are described below. Suppression of Th1 functions should shift the balance of Th1 versus Th2-mediated functions toward the Th2 cells. [50] Thus, VD should aggravate the Th2-mediated ...

Our results strongly suggest that Foxp3-induced IRF8 mediates Th1-like Treg cell function independent of T-bet. IRF8-deficient mice were described previously. 11 IRF8 fl/fl mice were purchased ...

leading to decreased levels of cAMP and increased production of prostaglandin and IL-10, which inhibit Th1 function and enhance IgE production. [41] ...

Their function in clearing specific types of infectious ... are the focus of important studies in immunology. Like Th1 and Th2 cells, Th17 cells produce a group of distinctive cytokines ...

This study highlighted some previously underappreciated functions of T cells that protect against viral skin infections. First, antigen-specific Th1 T EM CD4+ T cells provided protection and ...

"But in the past ten years we've realized that it's more important to have a T cell with long-lasting function. Th17 cells survive longer than Th1 cells because they have a more stem-like phenotype.