Neurofibrillary tangles (NFTs) are a hallmark of Alzheimer’s disease, formed by the accumulation of tau protein into ...

Detecting sites within that core region of 111 amino acids, a sequence they call tau 258-368, can identify clumping-prone tau proteins and help initiate further diagnostics and early treatment. In ...

These irregular clumps of protein are closely associated ... They showed that the presence of these phosphorylation sites, called p-tau-262 and p-tau-356, could predict future NFT production ...

Researchers say CSF biomarker test correlates with the severity of cognitive decline, independent of other factors, including brain amyloid deposition.

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering potential for timely intervention.

Researchers develop early Alzheimers diagnostic method using tau protein analysis Advancements in Alzheimers detection reveal ...

Arlette – stock.adobe.com Tau is a naturally occurring protein that helps stabilize nerve ... Karikari and his team pinpointed the primary site where tau molecules can abnormally bind together ...

Two main protein structures are associated with Alzheimer ... They showed that the presence of these phosphorylation sites, ...

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test can detect small amounts of the clumping-prone tau protein and its misfolded pathological forms ...

can identify clumping-prone tau proteins and help initiate further diagnostics and early treatment. In particular, the two new phosphorylation sites, p-tau-262 and p-tau-356, can accurately inform ...