In this context, immune cells called macrophages are a promising target in immuno-oncology, because tumour-associated macrophages (TAM macrophages) are immunosuppressive in most solid cancers, i.e ...

Correlation of enriched specific subset of immune cells nearby tumor associated macrophage (TAM) with pathologic complete response (pCR) of concurrent chemoradiotherapy followed by nivolumab in ...

22221 Background: Colony stimulating factor-1 (CSF-1) mediates macrophage (MØ) differentiation, proliferation, and survival through colony stimulating factor-1 receptor (CSF-1R, c-FMS, CD115). Tumor ...

Gastric cancer peritoneal metastasis (GCPM) remains a formidable clinical challenge, characterised by poor prognosis and limited therapeutic options. Despite the transformative impact of immune ...

The technology works by feeding macrophages tiny drops of a dye that can be detected by magnetic resonance imaging (MRI). The researchers will test the technology, called TAM-Sense, in patients ...

According to the scientists, beyond its use for cancer, TAM-Sense could also have clinical applications for other diseases that have substantial inflammatory components, such as autoimmune ...

Researchers at University of California San Diego School of Medicine have been awarded two new grants by the National Institutes of Health (NIH), totaling $6.7 million, to develop and clinically ...