What is TP53 and what role does it play in cancer? Medically reviewed by Marla Anderson, MD The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in ...

Discover the latest findings on transplantation outcomes in Myelodysplastic Syndrome and Acute Myeloid Leukaemia from EBMT ...

TP53 is the gene that encodes the p53 protein. p53 refers to the protein product of the TP53 gene. The traditional view of cancer development, driven by oncogene activation and tumor suppressor ...

A new study accessed the Mayo Clinic database to investigate the long-term survival of patients with myeloproliferative neoplasms and acute myeloid leukaemia associated with multihit TP53 ...

Mindrank Therapeutics (Suzhou) New Drug Research & Development Co. Ltd. has disclosed cellular tumor antigen p53 (TP53) (Y220C mutant) stabilizers reported to be useful for the treatment of cancer.

In many cancer types, the TP53 gene is often mutated or deleted, which inactivates the tumour suppression activity of the p53 protein. However, loss of p53 tumour-suppressor activity can also ...

SELLAS Life Sciences (SLS) announced Cohort 3 data from the ongoing Phase 2 trial of SLS009, a highly selective CDK9 inhibitor, in ...