In one study, a team of researchers led by Franck Barrat, Ph.D., found that two genetic receptors called TLR7 and TLR8, which ...

Imiquimod is an active substance that activates the innate receptors TLR7/8 and used to treat basal cell carcinomas. The researchers employed various preclinical mouse tumor models of melanoma and ...

However, IRAK4-dependent TLRs (TLR7, TLR8 and TLR9) appear to have a redundant role in protective immunity to most infections, including HSE. So why did the authors focus on TLR3? First ...