This represents the first time a mutation in the TLR7 gene has been directly linked to the onset of lupus, offering new ...

Miracure Biotechnology Ltd. has divulged Toll-like receptor 7 (TLR7) and/or TLR8 agonists reported to be useful for the treatment of cancer, infections, respiratory disorders and immunological ...

In one study, a team of researchers led by Franck Barrat, PhD, found that two genetic receptors called TLR7 and TLR8, which are present on the X chromosome, are important drivers for the ...

In one study, a team of researchers led by Franck Barrat, Ph.D., found that two genetic receptors called TLR7 and TLR8, which are present on the X chromosome, are important drivers for the ...

In one study, a team of researchers led by Franck Barrat, PhD, found that two genetic receptors called TLR7 and TLR8, which are present on the X chromosome, are important drivers for the ...

However, IRAK4-dependent TLRs (TLR7, TLR8 and TLR9) appear to have a redundant role in protective immunity to most infections, including HSE. So why did the authors focus on TLR3? First ...

TLR7 and TLR9 are also thought to be involved in B-cell-mediated production of autoantibodies specific to nucleic acids, thereby triggering and then promoting SLE. Barrat et al. have described ...

Introduction: The immune system protects against pathogens, and its dysfunction leads to primary and secondary immunodeficiencies, increasing infection susceptibility. Epstein-Barr virus (EBV) ...