Xin He, Mulan Chen, Yepeng Fan, Bin Wu, Zhifang Dong,TFE3-mediated neuroprotection: Clearance of aggregated α-synuclein and accumulated mitochondria in the AAV-α-synuclein model of Parkinson's ...

The study demonstrates that increasing TFE3 expression effectively enhances autophagy, the process by which cells remove misfolded proteins and damaged organelles. Through this mechanism, TFE3 ...

Studying the process of brain formation illuminates just how much of development is a series of tiny miracles. Only a few ...

Overall, Konopka and her colleagues found that human CLOCK regulates the expression of genes in neurons that contribute to the activation of other cells (i.e., excitatory neurons).