François and his student François Bourassa designed a theoretical mathematical model to determine how to modulate the immune response using receptors naturally present on the surface of T-cells.

An ICMR-funded trial led by CMC Vellore demonstrated that CAR-T therapy, which uses a patient's own T cells to fight cancer, ...

Researchers have developed a new method to grow T cells that have greater longevity and can more efficiently destroy cancer cells in mouse models of melanoma compared to those grown in traditional ...

CMC, Vellore trial shows that developing therapy in-house is feasible instead of relying on labs outside, can bring down ...

is one example of a complex animal model that has been successfully employed to model CAR T-cell immunotherapy in HER2+ breast cancer and is available off the shelf. 1 In one recent study using ...

Their lab was able to produce some of the first CD19-targeted CAR constructs and in 2003, they were the first to show that these CAR T-cells worked in a mouse model. “That was one of those first ...

Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies.

The classical model of the process was that one cell could ... Instead, he thinks when T cells cluster during activation, they may mosh so close to one another that their membranes partially ...

It develops from the abnormal multiplication of T cells, or T-lymphocytes, a type of white blood cell essential for immune system function. The specific treatment course and prognosis for T-cell ...