the GM mice without that receptor function had more active stem cells in the V-SVZ compared with unmodified mice. It was in these experiments that the gorditas cells appeared, as the newly ...

For the first time (in mice), a new article explains how baby neurons -- precursors called neuroblasts, generated from a permanent pocket of stem cells in a brain area called the V-SVZ -- make an ...

Sangram Sisodia and colleagues at the University of Chicago report that several PS1 mutants inhibit self-renewal and disturb differentiation of subventricular zone (SVZ) neural progenitor cells in the ...

Glutamic acid decarboxylase 65 (GAD65)- and Doublecortin (Dcx)-expressing cells constitute major progenitor populations in the adult mouse subventricular zone (SVZ). Under normal physiological ...

The researchers performed metabolomics and single cell RNA-seq in the V-SVZ of full-term birth mice and preterm birth mice. They found that normal term birth triggers RG to become quiescent ...

The researchers performed metabolomics and single cell RNA-seq in the V-SVZ of full-term birth mice and preterm birth mice. They found that normal term birth triggers RG to become quiescent ...

In order to understand them, they had to rely on mouse models. Although the human brain also has an SVZ, new neurons are only produced in the first year of life and this cell production is dormant ...