the researchers pinpointed Nr1h2 as a key transcription factor conserved across mammalian species. Nr1h2 activation was sufficient to enhance the functional and genetic fidelity of stem cell ...

In the study, the researchers used single-cell profiling and other techniques to analyze differences in gene activity between quiescent and activated blood stem cells. Eventually they zeroed in on FLI ...

A new process for converting skin cells to neurons directly could make it easier to develop therapies for neurodegenerative disorders.

THB-335 is an oral inhibitor of mast/stem cell growth factor receptor Kit (KIT), which regulates the activation and migration of mast cells, making it a relevant therapeutic target for inflammatory ...