However, spironolactone is associated with serious adverse events, including hyperkalemia and gynecomastia. [10,11] Consequently, clinical benefits related to the use of spironolactone are ...

Spironolactone-treated patients fared better than the placebo group, driven by the reduction in new or worsening heart failure. Roxana Mehran, MD (Icahn School of Medicine at Mount Sinai, New York, NY ...

Spironolactone is a generic prescription tablet that treats high blood pressure and other conditions. Learn about its side effects, uses, dosage, and more.

For this double-blind study, Kosiborod and colleagues enrolled 203 patients with HFrEF (New York Heart Association class II-IV; left ventricular ejection fraction ≤40%), optimal guideline ...

Because spironolactone is a diuretic, it can indeed cause a loss of water weight. This can be helpful for people who have certain conditions, but it may not be helpful for others.

Participants were randomized 1:1 to receive either 12.5 mg/d of spironolactone or 5 mg/d of amiloride. Dose escalation was permitted after four weeks for those with home SBP at or above 130 mm Hg ...

We enrolled 7062 patients at 104 centers in 14 countries; 3537 patients were assigned to receive spironolactone and 3525 to receive placebo. At the time of our analyses, the vital status was ...

According to a study in JAMA Dermatology, the prescribing rates of spironolactone for acne in women rose about 300% from 2017 to 2020. Here's what to know about spironolactone. IE 11 is not supported.

Background: Risk of morbidity and mortality in patients with severe heart failure (HF) is reduced by blockade of aldosterone receptors with spironolactone. However, benefits of spironolactone are ...