The flavonoid silymarin and one of its structural components, silibinin, are substances with documented hepatoprotective properties. Their mechanisms of action are still poorly understood.

One group of 25 patients received 200 mg of silymarin three times a day for 4 months, while the remaining 26 received a placebo treatment. All of the patients continued to use conventional oral ...

A new multicenter trial finds that taking silymarin (milk thistle) has no effect on serum ALT or levels of the hepatitis C virus in people with chronic hepatitis C infection. Silymarin or "milk ...

The mean lethal dose for rabbits and the maximum tolerated dose in dogs were calculated to be about 300 mg/kg. [6] These data demonstrate that the acute toxicity of silymarin is very low.

One group of 25 patients received 200 mg of silymarin three times a day for 4 months, while the remaining 26 received a placebo treatment. All of the patients continued to use conventional oral ...