A crucial mechanism in immune response: NOTCH signaling pathway plays essential role in CD8⁺ T cell differentiation
Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...
How Chickens Grew Dinosaur Feathers (Then Changed Back)
Feathers may have started as simple filaments in ancient dinosaurs, but a team of Swiss researchers is digging deep into the ...
EurekAlert!2d
Canonical and noncanonical NOTCH signaling in the nongenetic resistance of cancer: distinct and concerted control
Noncanonical signaling involves interactions with other pathways without RBPJ involvement. The NOTCH pathway contributes to ...
News-Medical.Net on MSN3d
New insights into therapy resistance in breast cancer
A new review was published in , Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer." ...
Calcium transport mechanism in wingless signaling pathway reshapes understanding of embryonic development
During embryonic development, the intestine of the Drosophila fly divides into distinct chambers thanks to the formation of ...
Neuroscience News7d
Sleep-Deprived Fruit Flies Show Sharper Memory via PKA Signaling
Fruit flies with genetic mutations that severely reduce sleep show enhanced performance in olfactory memory tasks, ...
EurekAlert!3d
PP2A regulates CD8+ T cell effector functions through AKT signaling pathway: implications for immunotherapy
A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...