Antibodies to DNA were demonstrated in the serums of patients with systemic lupus erythematosus (SLE) by ammonium sulfate precipitation. DNA is soluble in 50 per cent saturated ammonium sulfate, wh ...

Table 1 Association of SLE with non-HLA genes. SNPs are assigned to the nearest gene; the ideogram is given in the loc column ...

The new Biotage® Extrahera™ HV-5000, an automated workstation dedicated to column-based sample preparation that is able to aspirate and dispense high volume samples. Automation reduces reliance on ...

Systemic lupus erythematosus (SLE) is the most common type of lupus, a chronic autoimmune disease. Symptoms include fatigue, joint pain, and rashes across your nose and cheeks. While there’s no ...

The diagnosis of SLE is not always straightforward. The blood tests used as a screening test (such as the antinuclear antibodies and anti-double-stranded DNA antibodies) are not definitive.

Treatment for autoimmune diseases such as systemic lupus erythematosus (SLE), ... The asterisks in the columns for Patients 8, 11, and 15 reflect data at 3 months.

Systemic lupus erythematosus (SLE) is an autoimmune disease, in which the immune system that normally protects the body from invading microbes turns against the body's own cells. Researchers ...

The FDA has cleared an investigational new drug application for an allogeneic anti-CD19 chimeric antigen receptor T-cell therapy for the treatment of systemic lupus erythematosus with lupus ...

Many symptoms of SLE may develop after exposure to certain medications, as do similar antibodies in the blood. The most common symptoms of drug-induced lupus are fever, muscle and joint aches ...

The antimalarial hydroxychloroquine appears to protect against organ damage in patients with systemic lupus erythematosus, and the drug should be more widely prescribed in lupus, say US ...

Epidemiologic studies suggest a strong genetic component for susceptibility to systemic lupus erythematosus (SLE). To investigate the genetic mechanism of pathogenesis of SLE, we studied the ...