Rob Lowe opened up to PEOPLE about his late grandmother’s breast cancer journey and her success in a clinical trial. He’s now raising awareness for clinical trials in her honor.

Mark your calendars: In one week, Code Black is back! CBS’ medical drama is days away from launching its sophomore season, and there will be several new faces, most notably Rob Lowe, joining in ...

Rob Lowe reprised his role as the "Austin Powers" villain Number 2 in a new Super Bowl ad. Promoting Atkins protein chips, he told Insider he gets "starstruck" watching Mike Myers play Dr. Evil.

Rob Lowe makes a startling physical transformation in his role as plastic surgeon Dr. Startz in the HBO Liberace biopic Behind the Candelabra that premiered on Sunday. Although Douglas and Damon ...

Arnold Schwarzenegger is embracing his mid-life crisis by adopting a small zoo's worth of animals, his son Patrick revealed.

Rob Lowe appeared on the Today show on Monday ... “Al, you need to get a traveling facelift doctor,” Lowe quipped. “I mean, you got to have it.” Yet after all the kidding, Lowe got ...

Rob Lowe sees a similarity between the “nepo baby ... or becomes a second-generation doctor,” he explained. “So I don’t really see the novelty of it, but I understand it.” ...

Although Grey's was a much better script, I chose Dr. Vegas. The odds were just too stacked." Ah, hindsight. Maybe, if Lowe had played him, Derek Shepherd might even still be alive.

RELATED: Rob Lowe Makes His 'Code Black' Debut in Intense Season 2 Trailer Lowe, who most recently starred on Fox's short-lived comedy, The Grinder, plays Dr. Ethan Willis, a colonel attached to ...