This was no simple task, as the ribosome and its subunits represent the largest asymmetric structures solved by X-ray crystallography. Now, for the first time, double stranded RNA helices and the ...

“It’s a key advance in understanding ribosome [function] and also in establishing a path to fundamentally alter the catalytic center of the ribosome . . . which will really allow you to start ...

Ribosomes are composed of two subunits, the small and large subunits, each containing specific rRNA molecules. The main types of rRNA include: Small Subunit rRNA: In prokaryotes, the small subunit ...

Ribosomes undergo changes in conformational state, striking different, well-orchestrated poses that allow strands of RNA to be fed through the structure's two subunits where instructions carried ...

To test this, they isolated and centrifuged the ribosomes to separate their small and large subunits. Mendell and his team found that cells expressing SNORA13 produced fewer of the large subunit than ...

by determining the first complete structures of both eukaryotic ribosomal subunits each in complex with an initiation factor. Recently, his group also obtained a breakthrough in visualizing mammalian ...

These 70S ribosomes consist of two subunits: a 30S small subunit and a 50S large subunit. The 30S subunit contains a 16S ribosomal RNA (rRNA) molecule, while the 50S subunit harbors 23S and 5S ...