Jan. 16, 2025 – The breakthrough discovery of a powerful new gene editing tool called bridge RNAs has the potential to significantly advance gene therapy and usher in a new frontier in genome ...

Unravelling the complexities of circular RNAs (circRNAs) in cancer biology has positioned scientists on the cusp of revolutionary breakthroughs in the diagnosis and treatment of cancer.

Small RNAs are a type of non-coding RNA (ncRNA) molecule that are 50 250 nucleotides in length. They are often involved in regulating the translation of target RNAs through RNA RNA interactions.

In a new paper, researchers have investigated the role of small RNAs that help Salmonella express their virulence genes. Salmonella are food-borne pathogens that infect millions of people a year.

Significant numbers of small nucleolar RNAs (snoRNAs) are found in the nucleoli of eukaryotic cells. These small non-coding RNAs have a length of 60–300 nt and are encoded by the intronic ...

Deep sequencing has revealed thousands of eukaryotic protein-coding genes that defy the central dogma, producing circular noncoding RNAs rather than linear messenger RNAs. For some genes, the ...

University of Delaware’s Mona Batish is a molecular biologist. She studies circular RNAs formed as a result of so-called molecular mistakes that occur when a strand of RNA — the ribonucleic acid that ...

Biology textbooks have long preached the primacy of proteins, with RNAs the intermediary between code and final product, and scientists considered most noncoding RNAs to be useless junk, he explains. ...

In a review article, researchers have uncovered compelling evidence that long noncoding RNAs—molecules once dismissed as "junk DNA"—may hold the key to revolutionizing how we diagnose and ...