show that phase separation of the FOXM1 transcription factor is important for its oncogenic function and is inhibited by AMP-activated protein kinase ... including at FOXM1 binding sites, reduced ...
In neurodegeneration, e.g. MND, components of biocondensates are affected by mutations and are found within pathological protein aggregates ... when attached to disease-linked RNA-binding proteins, ...
A study published in Small highlights how nano-phase separation impacts analyte binding in aptasensors, paving the way for ...
Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...