A tophus can occur when you have gout and uric acid builds up around your joints. Larger tophi need to be removed so they don’t cause long-term damage.

Tophi are firm, painless yellow lesions that form in and around the joints in people with advanced gout. They have a uric acid (monosodium urate) core, and the skin that covers them can become ...

Tophi and Frequent Gout Flares Are Associated With Impairments to Quality of Life, Productivity, and Increased Healthcare Resource Use Results From a Cross-Sectional Survey.

Visually, gout can cause a joint to become red, swollen and shiny-sometimes even purple-and the skin may look stretched, ...

Gout symptoms in the toe, foot, knee, or ankle. Gout pain often starts in one joint. Your toe, foot, knee, or ankle are the most common spots to feel it.

Both excessive and long-term alcohol consumption, as well as any spirit consumption, predict the development of ultrasound-detected tophi and sub-tophi in patients with gout, according to data ...

I suffer from Gout and a day has not gone past since my 26th birthday that I have not had it in a joint somewhere. I have tried Puricos & Allomaron with no success. I have now developed Tophi on my ...

Gout flares are associated with cardiovascular events. Treating gout to target serum urate levels prevents flares, but ...

In a phase 2 global trial, 42 patients with gout and subcutaneous tophi were randomly assigned to receive once-daily AR882 (75 mg), AR882 (50 mg) plus allopurinol, or allopurinol alone (titrated ...

This study demonstrates that gout patients from the US and three EU countries suffer from significantly decreased HRQOL, with the average patient suffering decreased mental as well as physical ...

In a phase 2 global trial, 42 patients with gout and subcutaneous tophi were randomly assigned to receive once-daily AR882 (75mg), AR882 (50mg) plus allopurinol, or allopurinol alone (titrated up ...