Antibody-based therapeutics play a vital role in treating a wide range of diseases, but their manufacture can be complex, requiring efficient purification strategies to support product quality and ...

Recent advances in purification technology from ... A pure sample of protein is required to generate antibodies, conduct binding assays and study structure. Yet the target protein must first ...

The next generation of engineered monoclonal antibodies presents new challenges in downstream processing due to increased aggregate formation. These aggregates can compromise product efficacy, elevate ...

Tedious, time-consuming, exasperating: Those are perhaps the three words that researchers use most commonly to describe protein purification. Proteins, and their little sisters the peptides, are among ...

As an alternative to antibodies, proof-of-concept of the clinical efficacy of new protein scaffolds with different pharmacological properties and less expensive manufacturing processes might also ...

"Our study sheds new light on the relationship between the various structures of antibodies and their properties after protein translation," said FSU faculty researcher Fanny C. Liu, who was the ...

Because we produce recombinantly large amounts of different vascular-related proteins (such as VEGFs, their receptors, antibodies) using E. coli, yeast, insect cells, and mammalian cells, we started ...