Prince Frederik of Luxembourg died from a genetic disease called PolG, but experts hope his passing could bring more awareness to the rare condition that impacted his life. Prince Frederik ...

The son of Prince Robert of Luxembourg and Princess Julie of Nassau, Prince Frederik, has died in Paris the age of 22 due to a rare genetic disorder – POLG Mitochondrial disease. Frederik was ...

Prince Frederik of Luxembourg passed away from a rare mitochondrial condition affecting two of his POLG genes that he had been diagnosed with at the age of 14. His father, Prince Robert of ...

Now, researchers at the University of Gothenburg have discovered a small molecule that restores function in a defective mitochondrial enzyme, offering a new therapeutic avenue for diseases caused by ...

Researchers from Pretzel Therapeutics Inc. and the University of Gothenburg have published new insights on how mutations in the POLG gene affect its functionality and are tied to PolG diseases. They ...

One of the causes of these syndromes is a misbehaving mtDNA polymerase called POLG. Mutations or deletions in the gene for POLG yield defective polymerases that cannot stay on the mtDNA template ...