Prince Frederik of Luxembourg died from a genetic disease called PolG, but experts hope his passing could bring more awareness to the rare condition that impacted his life. Prince Frederik ...

His father announced his passing on March 7 in a statement posted on the website of the POLG Foundation, which Frederik cofounded in 2022 and was the creative director of. “Frederik fought his ...

Researchers at the University of Gothenburg have identified a small molecule, PZL-A, that restores function in the defective ...

Prince Frederik of Luxembourg passed away from a rare mitochondrial condition affecting two of his POLG genes that he had been diagnosed with at the age of 14. His father, Prince Robert of ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt cellular energy production.

Researchers from Pretzel Therapeutics Inc. and the University of Gothenburg have published new insights on how mutations in the POLG gene affect its functionality and are tied to PolG diseases. They ...

When the mechanisms that replicate or repair mitochondrial DNA (mtDNA) fail, it can cause a wide range of syndromes for which ...