Pfizer’s investigational therapy inclacumab failed to outperform a placebo in reducing vaso-occlusive crises in SCD patients ...

In someone with SCD, however, many of these red blood cells become sickle-shaped, hard, and sticky. These misshapen cells don’t flow smoothly through blood vessels.

Sickle cell disease (SCD) is a genetic disorder characterized by abnormal hemoglobin causing red blood cells to deform. Nutrition is crucial in managing SCD, as malnutrition and micronutrient ...

People with sickle cell disease may have a higher risk of developing blood cancer, but a lower risk for certain types of ...

The deformed cells can get stuck in small blood vessels, creating blockages that can reduce blood flow. SCD can cause painful episodes and strokes, and can damage organs including the lungs ...