In this multicenter, double-blind trial, we randomly assigned 3876 patients who had had a recent ischemic stroke or TIA to receive either pioglitazone (target dose, 45 mg daily) or placebo.

Chicago, IL-Results of a head-to-head comparison of two antidiabetes drugs have shown an advantage for pioglitazone (Actos, Takeda Pharmaceuticals North America) over glimepiride (Amaryl, Anakena ...

Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis of randomized trials. JAMA 2007; 298:1180-1188. Singh S, Loke YK, Furberg CD.

Both 15 mg and 30 mg pioglitazone doses have similar efficacy as 45 mg for preventing new-onset diabetes, stroke and myocardial infarction but with lower risk for adverse events, according to ...

Metformin/pioglitazone (Actoplus Met) is an oral drug used to treat type 2 diabetes. Learn about side effects, warnings, dosage, and more.

Pioglitazone and SGLT2 inhibitors as add-ons to insulin therapy were more effective for lowing HbA1c, fasting plasma glucose and insulin dose requirements in patients with type 2 diabetes than ...

The researchers found that the five-year risk for stroke or MI was 6.0% in the pioglitazone group compared with 7.9% in the placebo group, among patients with lower baseline risk (absolute risk ...

Among more than 91,000 newly-diagnosed diabetes patients ages 50 and older without a history of dementia, pioglitazone use was linked with a 16% lower risk for developing all-cause dementia ...

The study, titled “Efficacy of Lower Doses of Pioglitazone After Stroke or Transient Ischemic Attack in Patients With Insulin Resistance,” was published March 6 in the journal Diabetes, Obesity and ...

* A type 2 diabetes drug, pioglitazone, may reduce the risk of prostate cancer relapse by targeting the PPAR (and) #947; protein * Prostate cancer patients with diabetes on PPAR (and) #947; drugs ...

In conclusion, this study presents pioglitazone as a potential option to prevent skin ulcers in Werner syndrome patients. While further studies are needed, these findings provide hope for better ...