More than 100 patients have been vaccinated with epitope peptides derived from LAAs in the framework of Phase I/II clinical trials. No severe toxicities have been observed, but a high rate of ...
Tumors that develop in wild-type mice are more resistant because they have undergone serious immune editing and are able to overcome the immune system. Also, the study of vaccines cannot be ...
"Traditional peptide-based cancer vaccines, while safer than many alternatives ... hepatocellular carcinoma (HCC), the most common type of primary liver cancer. The LPH system demonstrated ...
such as peptide- or epitope-based vaccines, while others are cell-based, virus-based, or rely on RNA technology. According to Choueiri, there are pros and cons to each type of vaccine platform ...
Peptide vaccines have been improved by the inclusion of agonists of the Toll-like receptors, the expression of epitopes to induce by cytotoxic T cells (Tc) and T helper cells within the same ...
IO Biotech announced promising findings regarding a novel peptide vaccine designed to counter the immunosuppressive effects of Transforming Growth Factor Beta (TGF-β) in solid tumors. The ...
CARB-X (Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator) has announced it will award US$2 million to Immunethep SA to develop a conjugated peptide-based vaccine to prevent ...