Natural viral proteins cannot constantly be used as optimal vaccines because they do not always stimulate ... show that sequence modification of natural viral proteins to increase epitope affinity for ...
Our first-generation HER-2 peptide vaccines (316–339 and 628–647 ... the trastuzumab-binding epitope (597–626) and the pertuzumab-binding epitope (266–296). All four peptide sequences ...
Expert Rev Vaccines. 2009;8(10):1415-1425 ... For the three aforementioned antigens, more and more epitope peptides have been defined. Vaccination trials with truncated proteins covering ...
“By using an mRNA-based vaccine, you can encode an entire protein. That means you can expand the epitope range that your Trm cells are targeting,” Holz remarked. The team developed a novel vaccine ...
IO Biotech announced promising findings regarding a novel peptide vaccine designed to counter the immunosuppressive effects of Transforming Growth Factor Beta (TGF-β) in solid tumors. The ...
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Promising immunotherapy treatment targets multiple pathogenic hallmarks of Alzheimer's disease"What distinguishes our approach is that we're not just targeting one epitope in Alzheimer's ... A pentavalent peptide vaccine elicits Aβ and tau antibodies with prophylactic activity in an ...
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