PTP1B has also been linked to breast cancer both as a tumor suppressor and as an oncogene. Furthermore, PTP1B has been shown to be a regulator of cell adhesion and migration in normal and cancer ...

PTP1B expression and Gleason Score (GS) in localized prostate cancer (PC). Authors: Mauricio Mora Pineda, Shaddai Urbina Ramírez, Juan Hinojosa, Jazmin De Anda Gonzalez, Eucario Leon Rodriguez, and ...

These findings have identified PTP1B as an intracellular brake, or checkpoint, reminiscent of the cell surface checkpoint PD-1 - the blockade of which has revolutionized cancer therapy.

These findings have identified PTP1B as an intracellular brake, or checkpoint, reminiscent of the cell surface checkpoint PD-1 - the blockade of which has revolutionised cancer therapy.

Nicholas Tonks, Caryl Boies professor of cancer research at Cold Spring Harbor Laboratory (CSHL), and his team have found a drug candidate that can prevent lethal lung inflammation in mice by ...

Northridge Health Group (Hong Kong) Co. Ltd. has divulged proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to a tyrosine-protein ...

A groundbreaking new study led by researchers at the Masonic Medical Research Institute (MMRI) has identified a promising molecular target to protect the heart against damage caused by high-fat ...