Jnana’s lead program, JNT-517, is in development for phenylketonuria (PKU), an inherited disorder that leads to deficiency of an enzyme needed to break down phenylalanine, an amino acid found in ...

It was all for a good cause, though: Reynolds was climbing to raise awareness and research money for PKU, a rare disease that affects just 16,000 Americans. One of those affected people is ...

The test, part of newborn screening performed on babies across the U.S. led to my being diagnosed with a rare inherited disorder, phenylketonuria (PKU). I avoided intellectual disability and ...

Synthetic biology specialist Synlogic will start phase 3 testing of a drug for rare metabolic disorder phenylketonuria (PKU) next year, after reporting solid proof-of-concept data.

also known as PKU. This is a condition that causes a build-up of Phenylalanine, a building block of protein in the body. The disease is so rare there are fewer than 20,000 cases each year ...

Palynziq is already approved in the United States to reduce blood Phe concentration in adults aged 18 years and older with PKU. The drug is currently the only enzyme therapy to treat the disease ...

However, it can be dangerous for people with the genetic disorder phenylketonuria (PKU), which impairs the body’s ability to metabolize phenylalanine (5). Your body needs phenylalanine and other ...

“Eton brings valuable know-how in the metabolic space as well as commercialization expertise for products in rare diseases.” PKU is a rare inherited disorder caused by a defect in the enzyme ...

In the muddy trenches of World War I, thousands of soldiers on both sides fell ill with dysentery, a diarrheal disease often spread by contaminated water. Curiously, one German soldier deployed in ...