During development, cells grow, expand, and migrate to generate tissues and organs in a highly controlled manner. Many ...

WAYNE, PA — Palvella Therapeutics, Inc. (Nasdaq: PVLA), a biopharmaceutical company focused on developing treatments for rare ...

Exosomal RNAs, including miRNA, mRNA, and lncRNA, are secreted by tumor cells and play a pivotal role in cancer progression by modulating key signaling pathways such as NF-κB, EGFR, and PI3K/AKT ...

The laboratory is studying small molecules that selectively inhibit the components of RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. These compounds are being used as reagents to define the role of these ...

A fireside chat at the 24 th Annual Needham Virtual Healthcare Conference at 11:00 a.m. ET on Thursday, April 10, 2025. A live webcast will be available using this weblink: ...

One of these pathways is the PTEN / PI3K axis, a complex series of perfectly balanced chemical reactions. Mutations in the PTEN gene usually result in the overactivation of PI3K and the imbalance ...