Osteocalcin is necessary and sufficient to correct age-related decline in cognitive function in mice Mouse maternal osteocalcin contributes to brain development and the acquisition of cognitive ...

Here, the evidence for a role of osteocalcin in the regulation of glucose metabolism in humans is reviewed. Osteocalcin is a bone matrix protein that regulates hydroxyapatite size and shape ...

CI: Confidence interval; HbA1c: Glycated hemoglobin; I: Interventional study; IR: Insulin resistance; L: Longitudinal study; OR: Odds ratio; TOC: Total osteocalcin; X ...

The answer is osteocalcin, a hormone produced in the bones. Gerard Karsenty, a geneticist at the Columbia University Irving Medical Center, is one of the scientists behind this decades-long ...

After all, bone, through osteocalcin, contributes to energy metabolism, reproduction, memory, and the ability to exercise. Since all of these functions help animals survive hostile environments ...

Of the hormones on the list of bones’ messengers — osteocalcin, sclerostin, fibroblast growth factor 23 and lipocalin 2 — the last is the latest to attract attention. Lipocalin 2 ...

Their work has centered on osteocalcin, a hormone produced by some of the same cells that make up bone. His and others’ earlier research has suggested that osteocalcin helps regulate diverse ...

Although current evidence suggests that only a minuscule number of osteoblast-lineage cells are present in peripheral blood, we hypothesized that such cells circulate but that their concentration ...

Now a new hormone has entered the picture—osteocalcin, a protein produced and secreted by bone. Gerard Karsenty, a physician and geneticist at the Columbia University Irving Medical Center ...

In the mid-nineteen-nineties, a young French geneticist and physician named Gerard Karsenty became curious about a mysterious protein, called osteocalcin, that is found at high concentrations in ...

This section presents medications that are known to potentially lead to 'Osteocalcin increased' as a side effect. It's important to note that mild side effects are quite common with medications.

Deletion of the gene for the osteoblast-derived protein, osteocalcin, leads to insulin resistance in mice, while the addition of osteocalcin increases insulin secretion from β-cells and ...