They needed to find a functionally "orthogonal" pair­a tRNA/synthetase pair that react with each other but not with endogenous E. coli pairs. So they devised a methodology to evolve the ...

We announced dosing of the first patient earlier this year. Title: Engineered human IL-2/IL-2Rβ orthogonal pairs selectively enhance anti-GPC3 CAR T cells to drive complete responses in solid ...

Furthermore, says Mills, with the widespread adoption of CRISPR technologies, orthogonal validation is becoming more prevalent, especially in high impact journals. Another strong application of ...

Obtaining appropriate property data for an application sometimes necessitates the employment of both complimentary and orthogonal analytical methods. These terms illustrate how information from ...

They needed to find a functionally “orthogonal” pair?a tRNA/synthetase pair that react with each other but not with endogenous E. coli pairs. So they devised a methodology to evolve the ...