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News-Medical.Net on MSNUnmasking Nrf2 as a key driver of treatment resistance in osteosarcomaA deeper understanding of osteosarcoma , the most common primary malignant bone tumor affecting children and adolescents, is ...
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Techno-Science.net on MSNHorses have undergone a genetic mutation previously observed only in viruses 🐎Horses possess a rare genetic peculiarity. This adaptation partly explains their exceptional endurance without compromising their cellular health. A team of researchers has identified a ...
Reata Pharma has reported positive clinical results with one of its Nrf2 activators for mitochondrial diseases, just days after buying back rights from AbbVie. The positive data from a phase ...
Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms ...
Chemoresistance is the most significant challenge affecting the clinical efficacy of the treatment of patients with gastric cancer (GC). Here we reported that transmembrane protein 160 (TMEM160) ...
In his current research, Dr. Alvarez is investigating a metabolic pathway involving the transcription factor NRF2, a master regulator of the cellular antioxidant response, that can lead to metastatic ...
A deeper understanding of osteosarcoma, the most common primary malignant bone tumor affecting children and adolescents, is ...
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