The approval of gepotidacin (Blujepa; GSK) introduces the first new class of oral antibiotics for uncomplicated urinary tract ...

Study participants were randomly assigned to receive gepotidacin 1500mg twice daily or nitrofurantoin 100mg twice daily for 5 days. The primary endpoint for both trials was the combined clinical ...

Nitrofurantoin is an antibiotic that fights bacteria. It is used to treat and prevent uncomplicated urinary tract infections.

However, for some areas in England, nitrofurantoin resistance in urinary Escherichia coli (the most common cause of UTI) has recently risen to over 10%, bringing it close to levels where it can no ...