Singer and colleagues show that let-7 microRNAs target Zbtb16 mRNA, which encodes the transcription factor PLZF, to modulate PLZF expression during the terminal differentiation of NKT cells into ...

Accumulating evidence demonstrates that NKT cells can play important roles in the development of autoimmune and allergic diseases in mouse models. Although alterations in function and frequency ...

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with ...

Additionally, researchers found a correlation between higher antitumor activity and in vivo proliferation of infused CAR-NKT cells. “We cannot always predict the extent of NKT cell expansion in vivo ...

Contact: NKT Therapeutics Robert Mashal, President and CEO, 617-454-1008 [email protected] or Kureczka/Martin Associates Joan Kureczka, 415-821-2413 [email protected] ...